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Gee, when I go outside and see a bird fly or a VW bug go buy I'm am now wondering how likely it is that I am hallucinating, especially if many other people see the same thing. Not to say that some things aren't more or less able to be perceived. Blind people can't see birds and VW's and deaf people can't hear the effect of demagnetizing cd's. It's just life. A photo of my grainola clusters with blueberries and cashew milk is on the way, don't worry people. I must say I do like the flower and animal photos on my new IPS screen though. T456
"The Borg is the ultimate user. They're unlike any threat your Federation has ever faced."
- Q, 2365
Follow Ups:
IME especially oral history about warfare.
Warmest
Tim Bailey
Skeptical Measurer & Audio Scrounger
...much of the audiophile tweak world never gets past that point.
The fact that much of the audiophile world never gets past that point , that it is a very subjective hobby in many cases lends importance to actual experience and experimentation. If I needed a causal explanation for every tweek I wouldn't be where I am today. T456
"The Borg is the ultimate user. They're unlike any threat your Federation has ever faced."
- Q, 2365
Edits: 04/18/17
...the lack of consistent reproducibility in the tweak world (and the acceptance of this situation / tweaker complacency) relegates most tweaks to the fringes of the hobby, which, considering the fringe nature of the basic hobby in the first place............
Hahahahaha!
That was good!
:)
"much of the audiophile tweak world never gets past that point. "Or, as mhardy put it: Phase 1.
:)
Edits: 04/18/17
-- and must be considered in light of that.In my early "pro" days, I worked for a biotech company with an interesting anticancer immunotoxin "platform". Their original Phase 1 studies (which are used to assess the safety of a new drug, and not its efficacy) were conducted not in healthy volunteers but in (relapsed) cancer patients who had failed conventional therapies for their specific cancer.
Several of these very sick patients exhibited partial remissions after treatment with the drug, and there was at least one total remission.
The drug later failed to demonstrate efficacy in a standard Phase 2/3 protocol (cancer studies, at least in those days, were typically NOT placebo controlled, for rather obvious ethical reasons).
The PR and CR results in Phase 1 were anecdotal :-) The study wasn't designed to demonstrate, much less quantify, efficacy, and the drug was later shown NOT to be efficacious in an appropriately "powered" study.
BUT, for the folks who exhibited CR or PR, it WAS indeed efficacious.
Anecdotal evidence.
Not "false evidence" -- just difficult to interpret.The company in question later developed a different platform for immunotoxins and subsequently did develop effective cancer drugs.
all the best,
mrh
Edits: 04/18/17
Excuse me while I pick my jaw up off of the floor.
You did that sort of thing?! I'm impressed.
A little over a year ago, I told a nephew: "Pharmaceuticals." (Much as in the old film "The Graduate": "Plastics.")
:)
Still do some consulting.
Pretty satisfying line of work (despite the issues of cost to the payer).
all the best,
mrh
"Not "false evidence" -- just difficult to interpret." I would elaborate on your statement to say that many times it's difficult to interpret and many times it isn't , depending upon the situation. And many times it is actually false. T456
"The Borg is the ultimate user. They're unlike any threat your Federation has ever faced."
- Q, 2365
one doesn't know, e.g., if the CR was actually caused by the drug or that the correlation was simply coincidental .
As the statisticians love to say: correlation is not causation
all the best,
mrh
"correlation is not causation" More accurately would be to state that correlation is not necessarily causation. It may be or may not be. That is the question. T456
"The Borg is the ultimate user. They're unlike any threat your Federation has ever faced."
- Q, 2365
It took me a second, but then...
Hahahahahahahahahahaha!!
THAT is funny!
:)
"Do you see people that aren't there?"
My wife's response: "How would I know?"
"Once this was all Black Plasma and Imagination" -Michael McClure
Yo musetap, I think you have a keeper there.
"The Borg is the ultimate user. They're unlike any threat your Federation has ever faced."
- Q, 2365
If you witness an event, and testify under oath describing the event, it can be considered 'evidence'.
Others' testimony, who witnessed the same event, could be considered 'corroborating evidence'.
If the accounts vary substantially, the value of the 'evidence' decreases.
And vice-versa. :-)
SF
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